Predicting tolerance by counting natural regulatory T cells (CD4+25++FoxP+)?
نویسندگان
چکیده
منابع مشابه
Natural regulatory T cells and de novo-induced regulatory T cells contribute independently to tumor-specific tolerance.
Thymus-derived, naturally occurring CD4(+)CD25(+)Foxp3(+) regulatory T cells (nTregs) and Tregs induced in the periphery (iTregs) have both been implicated in regulating immune responses. However, the relationship between these populations in the same host, and their relative contribution to the overall Treg pool, has not been examined. Using a tumor-induced T cell tolerance model, we find that...
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ژورنال
عنوان ژورنال: Transplant International
سال: 2007
ISSN: 0934-0874,1432-2277
DOI: 10.1111/j.1432-2277.2007.00551.x